Four or more AudioFuse 16 as interface on mac

Hi at all here, i’m new here.

I working on an old mac pro 5.1, Logic Pro, Motu pci424 with 4x 24i/o.
I think to replace the audio i/o. Reason: new Apple mini M4 pro (?) for more power and current mac os. But in this way i can “trash” Motu.

Is it possible to connect 4 or more AudioFuse 16 to an Mac Mini M4, to use it as an large audiointerface? It means to build Core-Audio for using all the i/o. Maybe it must work on a usb-hub.

Any experince or advices in this case?

Thank you a lot!
dr.squ
from www.deepsonic.ch