Every time I restart the Analog Lab software all my midi inputs are active. I uncheck the ones i do not need and keep my Analogue Laboratory checked and I can play sounds. Once I quit and reopen, the midi inputs revert to all of them being on and does not save my prior selection.
This is since the upgrade to the new version in V Coll 4.
I also noticed that once I upgraded, all my audio sound card prefs had disappeared on all synths and I had to re-input them for all applications of V Coll V 4.