@Kceal this issue isn't about the hardware unfortunately. As @rchrdk pointed out "the software opens in "multi" mode and won't respond to any mouse input". The entire interface just stays frozen. I've just tried @Adrien's suggestion and Lo and Behold I can finally take this baby for a test drive without having to change my workflow.
Anywho, go to your Native Instrument folder, select Maschine's App icon and bring up its info window by clicking the information icon on your toolbar or typing (Command & the letter i), uncheck the box that says "Open in 32-bit mode". The next time you open Maschine and run Analog Lab you'll be able to switch presets and generally interact with the software.