I have Mac OSX 10.6.8 and Cubase LE4. A few days ago I updated my Overheim SEM-V to 1.1.6. I didn't notice any difference until I opened an SEM-V patch within Analog Laboratory and tried to open SEM-V through Laboratory (for editing purposes) and all I got was a white window instead of the gui of the SEM-V. Re-booted twice, same problem. I reverted back to SEM-V 1.1.5, had to re-boot a few times before things were back to normal. Through Cubase LE4 Device Manager update thing, I also had to update the SEM-V. Also had to open SEM-V as a stand-alone first before everything worked again. Didn't do an un-install (didn't know how), not sure if that made a difference reverting back to 1.1.5.