Let's start with the first step.
When you loaded your VST into an empty project, can you tell me if you did so manually, setting up the midi/audio I/O settings as you enabled it, or, did you open up a previously set up track template?
I want to determine if you have that set up as it should be first, as that can contribute to everything else down the chain.
What "host" have you made this attempt with, specifically.
I have an idea what may be contributing to your volume issue, but I want to verify something first.
Also, let me know if your Laboratory 49 is working fine in Stand Alone mode, meaning, now DAW involved.